• Devi Ratnasari Sekolah Tinggi Teknologi Industri dan Farmasi Bogor
  • Effionora Anwar Departemen Farmasetika, Fakultas Farmasi, Universitas Indonesia
Keywords: Flavonoid, Nanovesicle, Rutin, Transdermal, Transfersom


Transdermal become the alternative to deliver low solubility compound and low bioavalibility when given orally. Rutin is a flavonoid compound are found in watermelon and citrus. Rutin shows a low absorption when administered orally so the alternative is given in the transdermal route. A variety of approaches taken to increase the penetration of transdermal, one with nanovesikel carrier system. Transfersome is nanovesicle 200-300 nm sized composed of phospholipids, surfactants and water to increase penetration in trasndermal route. This study was to characterization transfersome containing rutin. The result show the size of transfersome < 150 nm, polydispersity index about 0.1 to 0.3, zeta potential less than -30 mV and entrapment efficiency > 80%.


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How to Cite
Devi Ratnasari, & Effionora Anwar. (2016). KARAKTERISASI NANOVESIKEL TRANSFERSOM SEBAGAI PEMBAWA “RUTIN” DALAM PENGEMBANGAN SEDIAAN TRANSDERMAL. Jurnal Farmamedika (Pharmamedika Journal), 1(1), 12-18. https://doi.org/10.47219/ath.v1i1.40