PERBANDINGAN PENURUNAN TEKANAN DARAH PASIEN BEDAH FRAKTUR DENGAN PREMEDIKASI ANESTESI PETIDIN DAN FENTANIL DI RSUD KOTA BOGOR

  • Siti Mariam Sekolah Tinggi Teknologi Industri dan Farmasi Bogor
  • Kiki Fitriana Dewi Sekolah Tinggi Teknologi Industri dan Farmasi Bogor
  • Halimatussa’diyah Sekolah Tinggi Teknologi Industri dan Farmasi Bogor
Keywords: Anesthesia, Fentanyl, Phetidine, Decrease in Blood Pressure

Abstract

Premedication of intravenous anesthesia using the drugs petidine and fentanyl causes side effects of hypoventilation or decreased tidal volume and hypotension. This study aims to determine the decrease in blood pressure in fracture surgery patients at RSUD Kota Bogor. This study was conducted on 100 inpatients in the January-December 2018 period who were given the drugs petidine and fentanyl premedication. This type of non-experimental research with the retrospective data collection, research data were analyzed using the Kolmogorov-Sminorv test and the Mann Whitney test. Data taken included: Medical record number, age, sex, duration of surgery and blood pressure 5 minutes before premedication to 1 hour of surgery. The results found more surgical fracture patients occur in men (63%) with an age range of 40-50 years (29%). The duration of the most operations was 1 hour (62%). The most widely used premedication therapy as a narcotic analgesic drug is fentanyl (70%). The most common decrease in blood pressure is petidine (13.93 mmHg) compared to fentanyl (8.34 mm / Hg). Based on statistical results using the Kolmograv-Smirnov test and the Mann-Whitey test p-value (asymp sig. (2-tailed) showed a p-value of 0.05 (0,000) which means that there is a difference in blood pressure reduction between petidine and fentanyl.

References

[1]Absalom, A.R., Struys, M. Overview of Target Controlled Infusions and Total Intravenous Anaesthesia. Edisi ke 2. 2007. English: Academia Press. 2. Absalom, A. R., Sutcliffe N., Kenny.
[2] Annisa, Fadhlina (2010), Perbandingan Perubahan Tekanan Darah Dan Laju Nadi Antara Pemberian Petidin dan Fentanil Sebagai Premedikasi Anestesi (Skripsi) Universitas Sebeles Maret Surakarta.
[3] Arvianto dkk, 2017, Perbandingan antara Sevofluran dan Propofol Menggunakan Total Intravenous Anesthesia Target Controlled Infusion terhadap Waktu Pulih Sadar dan Pemulangan Pasien pada Ekstirpasi Fibroadenoma Payudara, Jurnal Anestesi Perioperatif [JAP. 2017;5(1): Departemen Anestesiologi dan Terapi Intensif Fakultas Kedokteran Universitas Padjadjaran/Rumah Sakit Dr. Hasan Sadikin Bandung.
[4] Boulton T., Blogg C., 1994. Komplikasi dan Bahaya Anestesi: Anestesiologi. EGC. Jakarta: 229-231.
[5] Dinas Kesehatan, 2010. Pethidin. http://www.diskes.jabarprov.go.id.
[6] Dinas Kesehatan, 2010. Phentanyl. http://www.diskes.jabarprov.go.id.
[7] Gwinutt C., 1997. Drugs Asociated with Anaesthesia. Measurement andMonitorng : Clinical Anaesthesia. University of Manchester. Oxford. Hlm: 53-54 ; 79-84.
[8] Holder A. Sedation. Diunduh dari: http:// emedicine.medscape.com/ article/ 809993-overview#showall Diakses : Agustus 2012 3Malinowska M., et al., 1998. Influence of propofol and Ketamin in TIVA Laparoscopic Surgery on some Haemodynamic and Biochemical Stress Reaction Parameters.Med Sci Monit: 661-664
Published
2019-06-12
How to Cite
Siti Mariam, Kiki Fitriana Dewi, & Halimatussa’diyah. (2019). PERBANDINGAN PENURUNAN TEKANAN DARAH PASIEN BEDAH FRAKTUR DENGAN PREMEDIKASI ANESTESI PETIDIN DAN FENTANIL DI RSUD KOTA BOGOR. Jurnal Farmamedika (Pharmamedika Journal), 4(1), 18-22. https://doi.org/10.47219/ath.v4i1.54